Publication

  1. Ding H, Zhao J, Zhang Y, Yu J, Liu M, Li X, Xu L, Lin M, Liu C, He Z, Chen S, Jiang H. Systematic analysis of drug vulnerabilities conferred by tumor suppressor loss. (2019) Cell Reports 27,3331-3344. (Corresponding author)

  2. Li X, Zhang Y, Zheng L, Liu M, Chen CD, Jiang H. UTX is an escape from X-inactivation tumor-suppressor in B cell lymphoma. (2018) Nature Communications. 9(1):2720. (Corresponding author)

  3. Liu C, Ding H, Li X, Pallasch CP, Hong L, Guo D, Chen Y, Wang D, Wang W, Wang Y, Hemann MT, Jiang H. A DNA/HDAC dual-targeting drug with significantly enhanced anticancer potency. (2015) EMBO Molecular Medicine, 7(4):438-49. (Corresponding author)

  4. Wang N, Ding H, Liu H, Li X, Wei L, Yu J, Liu M, Ying M, Gao W, Jiang H* , Wang Y*. A novel recurrent CHEK2 Y390C mutation identified in high risk Chinese breast cancer patients impairs its activity and is associated with increased breast cancer risk. (2015) Oncogene, 34(40):5198-205 (*Corresponding author)

  5. Wu J#, Jiang H#, Luo S#, , Zhang M, Zhang Y, Sun F, Huang S and Li H. Caspase-mediated cleavage of C53/LZAP protein causes abnormal microtubule bundling and rupture of the nuclear envelope. (2013) Cell Res, 23(5):691-704. (#equal contribution)

  6. Jiang H, Pritchard JR, Williams RT, Lauffenburger DA, Hemann MT. A mammalian functional-genetic approach to characterizing cancer therapeutics. (2011) Nat Chem Biol. 7(2):92-100. (First author)

  7. Reinhardt HC#, Jiang H#, Hemann MT and Yaffe MB. Exploiting synthetic lethal interactions for targeted cancer therapy. (2009) Cell Cycle 8(19) :3112-9. (#equal contribution)

  8. Jiang H#, Reinhardt HC#, Bartkova J, Tommiska J, Blomqvist C, Nevanlinna H, Bartek J, Yaffe MB, Hemann MT. The combined status of ATM and p53 link tumor development with therapeutic response. (2009) Genes Dev. 23(16):1895-909. (First author)

  9. Jiang H#, Wu J#, He C, Yang W, Li H. Tumor suppressor protein C53 antagonizes checkpoint kinases to promote cyclin-dependent kinase 1 activation. (2009) Cell Res. 19(4):458-68. (First author)

  10. Jiang H, Luo S, Li H. Cdk5 activator-binding protein C53 regulates apoptosis induced by genotoxic stress via modulating the G2/M DNA damage checkpoint. (2005) J Biol Chem. 280(21):20651-9. (First author)